Mansi Parekh, Ph.D.
Biomedical Sciences Building
Biomedical Sciences Building, Room J351
- Ph.D., University of Florida (2010)
My research focuses on brain structural changes that take place during epileptogenesis. I use high resolution MRI data from both a rat model of epilepsy as well as patients with epilepsy to study the evolution of the epileptic network, both gray and white matter. Based on my graduate research, we have shown that early damage post status epilepticus in the parahippocampal gyrus is unique to rats that later develop spontaneous seizures. The current focus of my research is to study white matter connectivity changes in patients with epilepsy and to correlate them with neuropsychology and functional EEG abnormalities.
I was born in India but grew up in Nairobi, Kenya. I joined the University of Florida in 2001 to pursue a bachelor’s degree in Chemistry. After completing my bachelors with highest honors in 2005, I enrolled in the PhD program through the College of Medicine. I graduated with a PhD in neuroscience under the mentorship of Dr. Thomas H. Mareci and Dr. Paul R. Carney in 2010. I am currently pursuing a post-doc with Dr. Paul Carney to continue and enhance some of the work performed during my graduate studies.
- Cadotte A., Mareci T., DeMarse T., Parekh M.B., Rajagovindan, R., Ditto W., Talathi S.S., Hwang D., Carney P.R., Temporal Lobe Epilepsy: Anatomical and Effective Connectivity, IEEE Trans on Neural Systems and Rehabilitation Engineering; 17(3) 2009; pg 214-223
- Cadotte A., DeMarse T., Mareci T., Parekh M.B., Talathi S.S., Hwang D., Ditto W., Ding M., Carney P.R., Granger Causality Relationships between Local Field Potentials in an Animal Model of Temporal Lobe Epilepsy (Accepted 2010, Journal of Neuroscience Methods)
- Parekh M.B., Carney P.R., Sepulveda H., Norman W., King M.A., Mareci T.H. Early MR Diffusion and Relaxation Changes in the Parahippocampal Gyrus Precede the Onset of Spontaneous Seizures in an Animal Model of Chronic Limbic Epilepsy, Experimental Neurology 224 (2010), pp. 258-270
- Cheng G., Vemuri B.C., Parekh M.B., Carney P.R., and Mareci T.H. Diffeomorphic symmetric registration of high angular resolution diffusion MR images represented by Gaussian mixture fields, IEEE Transactions on Medical Imaging, submitted.